Which Companies Have Recently Expanded Into the City of Phoenix

Mayo Clinic announced a $1.9 billion expansion of its north Phoenix campus on March 3, 2025, adding 1.2 million square feet, 48 patient beds, 11 operating rooms, and 3,500 new jobs.

On March 24, 2026, Phoenix Mayor Kate Gallego and City Council approved a $50 million city investment — the largest direct city contribution ever to a single bioscience project — for ASU Health's new downtown medical school at the Phoenix Bioscience Core.

McCarthy Building Companies, a 100%-employee-owned national builder, signed a nearly-100,000-square-foot lease at 3133 E. Camelback Road to relocate and expand its Phoenix regional headquarters, reported July 10, 2026, with opening slated for late 2027.

Exact Sciences (maker of the Cologuard cancer-screening test) is building a 250,000-square-foot lab, office, manufacturing and warehouse facility on 17 acres at Sky Harbor Center near Phoenix Sky Harbor International Airport, projected to create more than 800 jobs.

Aerospace and defense electronics manufacturer Mercury Systems is expanding its existing Phoenix manufacturing operations by roughly 50,000 square feet, adding more than 50 jobs, according to an October 13, 2026 report.

Visit Phoenix, the city's tourism bureau, signed a 24,722-square-foot lease at 1 E. Washington St. in the CityScape tower in downtown Phoenix for its new headquarters, announced February 4, 2025, with move-in planned for Q4 2025.

Phoenix's Community and Economic Development Department tracks the city's relocation and expansion wins on Invest in Phoenix — start here to see how the city partners with growing employers.