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Differential mosquito attraction to humans and skin acids
Mosquito attraction to humans varies significantly based on individual differences in skin odor composition, particularly elevated carboxylic acids in highly attractive individuals. Genetic mutations in chemosensory receptors (Ir8a, Ir25a, Ir76b) impair mosquito attraction to human scent, suggesting these compounds are key to differential mosquito preference and could inform repellent development.
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Summary
Mosquito attraction to humans varies significantly based on individual differences in skin odor composition, particularly elevated carboxylic acids in highly attractive individuals. Genetic mutations in chemosensory receptors (Ir8a, Ir25a, Ir76b) impair mosquito attraction to human scent, suggesting these compounds are key to differential mosquito preference and could inform repellent development.
Tags
mosquito-attraction · skin-odor · chemosensory-receptors · carboxylic-acids · olfaction · metabolomics
Key entities
Aedes aegypti (organism, 0.95) · chemosensory-receptors (concept, 0.92) · carboxylic-acids (concept, 0.9) · skin-odor (concept, 0.93) · olfaction (concept, 0.88) · Orlando (location, 0.75) · Liverpool (location, 0.75)
Classification
reference · language en · status final
Provenance
claude-haiku-4-5 via @stacklist/be@0.1.0, confidence 0.85, 21 Jul 2026