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See all stacks →Caffeine: How much is too much? - Mayo Clinic
Caffeine consumption guidelines recommend up to 400mg daily for most adults, equivalent to four cups of coffee, but excessive intake can cause serious side effects including insomnia, anxiety, and heart palpitations. The article provides guidance on when to reduce caffeine intake, potential drug interactions, and strategies for safely cutting back while managing withdrawal symptoms.
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Summary
Caffeine consumption guidelines recommend up to 400mg daily for most adults, equivalent to four cups of coffee, but excessive intake can cause serious side effects including insomnia, anxiety, and heart palpitations. The article provides guidance on when to reduce caffeine intake, potential drug interactions, and strategies for safely cutting back while managing withdrawal symptoms.
Tags
caffeine · health-guidelines · safe-consumption · side-effects · medication-interactions · sleep-health
Key entities
Mayo Clinic (organization, 0.99) · U.S. Food and Drug Administration (organization, 0.99) · caffeine toxicity (concept, 0.95) · caffeine withdrawal (concept, 0.94) · insomnia (concept, 0.92) · medication interactions (concept, 0.9)
Classification
reference · language en · status final
Provenance
claude-haiku-4-5 via @stacklist/be@0.1.0, confidence 0.85, 30 Aug 2026