{"version":"1.0","type":"card","id":"d08a2c1a-2403-46b1-96e3-6950715466b4","url":"https://stacklist.com/card/d08a2c1a-2403-46b1-96e3-6950715466b4","title":"Who Should Go Easy on Caffeine: The Anxiety Data","source_url":"https://pubmed.ncbi.nlm.nih.gov/34871964/","note":"Meta-analysis in General Hospital Psychiatry: high caffeine doses, around five cups of coffee, triggered panic attacks in about half of people with panic disorder. Know your own sensitivity.","image":{"url":"https://ucarecdn.com/c0b765fe-b54e-4561-9c0f-9ee3cbf3ec9a/","alt":"Who Should Go Easy on Caffeine: The Anxiety Data","width":1440,"height":810},"stack":{"id":"ed5a3ae2-37d9-4b9f-acfb-16fc78c07ec8","title":"Calm Focus for Finals: LSC100 + Studying, Exam Season & ADHD Focus","url":"https://stacklist.com/c/education/stack/ed5a3ae2-37d9-4b9f-acfb-16fc78c07ec8"},"created_at":"2026-11-02T22:10:51.702Z","updated_at":null,"aco":{"summary":"This systematic review and meta-analysis examines the acute effects of caffeine on panic attacks and anxiety in patients with panic disorder versus healthy controls. Results show that caffeine at doses equivalent to 5 cups of coffee induces panic attacks in over half of panic disorder patients compared to only 1.7% of healthy controls, with increased anxiety sensitivity observed in the patient group.","tags":["caffeine","panic-disorder","anxiety","meta-analysis","placebo-controlled","dose-response"],"key_entities":[{"name":"panic disorder","type":"concept","confidence":0.99},{"name":"caffeine challenge","type":"concept","confidence":0.98},{"name":"anxiety","type":"concept","confidence":0.99},{"name":"placebo-controlled study","type":"concept","confidence":0.97},{"name":"meta-analysis","type":"technology","confidence":0.98},{"name":"PROSPERO","type":"organization","confidence":0.95},{"name":"dose-response relationship","type":"concept","confidence":0.96}],"classification":"analysis","language":"en","confidence":0.85,"provenance":{"model":"claude-haiku-4-5","tool":"@stacklist/mcp-server@2.0.0","confidence":0.85,"timestamp":"2026-11-02T22:10:57.116Z"},"token_counts":{"approximate":1029,"cl100k":812},"content_hash":"sha256:fd30b9eb29c1407d529b182f2872607c6cafee66b0f3ece574b428fcaf429cbf","acp_version":"0.2","body_available":true,"body_tokens":1029,"visibility":"public","agent_accessible":true,"status":"final"},"_links":{"self":"/api/public/card/d08a2c1a-2403-46b1-96e3-6950715466b4.json","html":"https://stacklist.com/card/d08a2c1a-2403-46b1-96e3-6950715466b4","md":"/api/public/card/d08a2c1a-2403-46b1-96e3-6950715466b4.md","stack_json":"/api/public/stack/ed5a3ae2-37d9-4b9f-acfb-16fc78c07ec8.json"}}