---
title: "L-Theanine + Caffeine Beat Caffeine Alone on Attention"
url: https://stacklist.com/card/c9cf6726-e89a-470a-a2e7-40634ba11ea1
source_url: "https://pubmed.ncbi.nlm.nih.gov/18681988/"
stack: https://stacklist.com/c/education/stack/ed5a3ae2-37d9-4b9f-acfb-16fc78c07ec8
summary: "L-Theanine combined with caffeine improves attention-switching performance and reduces distractibility more effectively than caffeine alone in healthy volunteers. The study compared 50 mg caffeine with and without 100 mg L-theanine across multiple cognitive tasks, demonstrating synergistic benefits for cognitively demanding performance."
tags: "caffeine, l-theanine, attention, cognition, drug-interaction, clinical-trial, cognitive-performance"
key_entities: "L-Theanine (concept), Caffeine (concept), Attention-switching task (concept), Cognitive performance (concept), Drug interaction (concept), Rapid visual information processing (concept)"
classification: "reference"
content_hash: "sha256:d20b7b58937c79849c2704b47f79c5513478cf875e98e819e15d3741a94f31f4"
acp_version: "0.2"
token_counts_approximate: 680
visibility: public
agent_accessible: true
status: "final"
---

# L-Theanine + Caffeine Beat Caffeine Alone on Attention

Full text links Cite Display options Display options Format Abstract PubMed PMID Linked Discoveries Abstract The aim of this study was to compare 50 mg caffeine, with and without 100 mg L-theanine, on cognition and mood in healthy volunteers. The effects of these treatments on word recognition, rapid visual information processing, critical flicker fusion threshold, attention switching and mood were compared to placebo in 27 participants. Performance was measured at baseline and again 60 min and 90 min after each treatment (separated by a 7-day washout). Caffeine improved subjective alertness at 60 min and accuracy on the attention-switching task at 90 min. The L-theanine and caffeine combination improved both speed and accuracy of performance of the attention-switching task at 60 min, and reduced susceptibility to distracting information in the memory task at both 60 min and 90 min. These results replicate previous evidence which suggests that L-theanine and caffeine in combination are beneficial for improving performance on cognitively demanding tasks. PubMed Disclaimer Publication types Randomized Controlled Trial Actions Search in PubMed Search in MeSH Add to Search MeSH terms Adult Actions Search in PubMed Search in MeSH Add to Search Affect / drug effects* Actions Search in PubMed Search in MeSH Add to Search Attention / drug effects Actions Search in PubMed Search in MeSH Add to Search Caffeine / administration & dosage* Actions Search in PubMed Search in MeSH Add to Search Cognition / drug effects* Actions Search in PubMed Search in MeSH Add to Search Cross-Over Studies Actions Search in PubMed Search in MeSH Add to Search Double-Blind Method Actions Search in PubMed Search in MeSH Add to Search Drug Interactions Actions Search in PubMed Search in MeSH Add to Search Female Actions Search in PubMed Search in MeSH Add to Search Flicker Fusion Actions Search in PubMed Search in MeSH Add to Search Glutamates / administration & dosage* Actions Search in PubMed Search in MeSH Add to Search Humans Actions Search in PubMed Search in MeSH Add to Search Male Actions Search in PubMed Search in MeSH Add to Search Placebos Actions Search in PubMed Search in MeSH Add to Search Time Factors Actions Search in PubMed Search in MeSH Add to Search Substances Glutamates Actions Search in PubMed Search in MeSH Add to Search Placebos Actions Search in PubMed Search in MeSH Add to Search Caffeine Actions Search in PubMed Search in MeSH Add to Search theanine Actions Search in PubMed Search in MeSH Add to Search LinkOut - more resources Full Text Sources Atypon Other Literature Sources The Lens - Patent Citations Database Medical ClinicalTrials.gov MedlinePlus Health Information