---
title: "Allulose and the Glycemic Index"
url: https://stacklist.com/card/238b76fc-ae7d-4877-b529-5d7b14380484
source_url: "https://allulose.org/allulose-professionals/latest-science/glycemic-index/"
stack: https://stacklist.com/c/food/stack/72143e0f-7dc1-462a-9cdd-2bc70e459b04
summary: "Allulose, a non-nutritive sweetener, has been shown in multiple clinical studies to have no impact on blood glucose and to suppress glycemic response when co-ingested with other carbohydrates. Three highlighted studies using crossover designs in healthy and borderline-diabetic adults consistently found that allulose is non-glycemic and may reduce postprandial blood glucose and insulin responses."
tags: "allulose, glycemic-index, blood-glucose, non-nutritive-sweetener, diabetes, clinical-studies, postprandial-response"
key_entities: "Allulose (concept), Glycemic Index (concept), Tate & Lyle (organization), FDA (organization), GRAS (concept), Glycemic Index Laboratories (organization), Toronto (location), Jill Weisenberger (person), D-psicose (concept), Postprandial Blood Glucose (concept), IFT19 (event)"
classification: "reference"
content_hash: "sha256:d8fa29be41e62c9ca5ebb5a5cb1e0d1c6a00ce7b1efda4333ca4be1f2086ab5b"
acp_version: "0.2"
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visibility: public
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status: "final"
---

# Allulose and the Glycemic Index

Allulose has no impact on blood glucose In conducting studies as part of the GRAS process, researchers found that the non-nutritive sweetener allulose has no impact on blood glucose and actually suppresses glycemic response of other glycemic carbohydrates when tested with carbohydrates or within a meal. When tested as a single ingredient, allulose is shown to be non-glycemic. Three studies highlighted below used various scientific models and found the same conclusion — allulose does not impact blood sugar: In a crossover study with 20 healthy adults after an overnight fast, 7.5 g of allulose intake did not influence blood glucose or insulin concentration; 5 and 7.5 g of allulose intake suppressed glycemic response (postprandial blood glucose) and insulinemic response (postprandial insulin) of 75 g of co-ingested maltodextrin [6].6. Iida T, Kishimoto Y, Yoshikawa Y, Hayashi N, Okuma K, Tohi M, Yagi K, Matsuo T, Izumori K. Acute D-psicose administration decreases the glycemic responses to an oral maltodextrin tolerance test in normal adults . J Nutr Sci Vitaminol (Tokyo) 2008; 54:511-514. Another clinical study tested 5 g allulose in tea with a standard meal after an overnight fast in 15 adults diagnosed with borderline diabetes and 11 adults with normal glycemia. This treatment suppressed glycemic response (postprandial glucose) but not insulinemic response (postprandial insulin) of the standard meal in subjects with normal glycemia and in those with borderline diabetes compared to a meal without allulose [7].7. Hayashi N, Iida T, Yamada T, Okuma K, Takehara I, Yamamoto T, Yamada K, Tokuda M. Study on the postprandial blood glucose suppression effect of D-psicose in borderline diabetes and the safety of long-term ingestion by normal human subjects . Biosci Biotechnol Biochem 2010; 74:510-519. In another human pilot study supported by Tate & Lyle, an allulose manufacturer, ten healthy adults were given 25 g allulose or 25 g glucose in a cross-over design after a 12 to 14 hour fast. Results showed that when subjects consumed allulose, blood glucose response did not rise above baseline for two hours following the dose. [8]8. Kendall C, Wolever T, Jenkins A et al. Glycemic Index Laboratories, Toronto, Canada. May 2014. Learn More Brain Activity & Connectivity Changes: Response to Natural Sugar Replacements & Artificial Sweeteners – Nutritional Neuroscience ARTICLE: Brain activity and connectivity changes in response to nutritive natural sugars, non-nutritive natural sugar replacements and artificial sweeteners AUTHORS: ... Read More IFT19 showcases solutions for clean-label trends – Beverage Industry The Institute of Food Technologists (IFT) Annual Expo highlighted the latest innovations impacting the food and beverage markets. Tate & ... Read More Tate & Lyle talks allulose: The first two things consumers look for are calories and sugar – Food Navigator Allulose has 90% fewer calories than table sugar and is now attracting the attention of mainstream consumer packaged goods brands, ... Read More Initial sales of low-carb cereal Magic Spoon have exceeded expectations – Food Navigator Sales of new keto-friendly cereal Magic Spoon have exceeded expectations, say founders Gabi Lewis and Greg Sewitz, who claim to ... Read More FDA Exempts Allulose from Added Sugar Labeling Requirements April 17, 2019 -- For the first time, the U.S. Food and Drug Administration (FDA) is allowing an ingredient chemically ... Read More Study Finds Anti-Obesity Potential of Allulose By Jill Weisenberger, MS, RDN, CDE, CHWC, FAND Allulose, also known as D-psicose, is a rare sugar originally discovered naturally ... Read More Importance of Clear Nutrition Information for Diabetes Management: Spotlight on Allulose April 25, 2019 -- While some people ignore or merely glance at the nutrition information on food and beverage packaging, ... Read More Allulose & the New Nutrition Facts Label October 29, 2018 -- Although the U.S. Food and Drug Administration (FDA) extended the dates for food and beverage companies ... Read More Rare Sugars: Demystifying Diamonds in the Rough You’ve heard terms like “raw” and “natural” to describe low calorie sweeteners, but what about “rare”? As the name suggests, ... Read More Allulose: A Sweet New Tool for Diabetes Management By: Melissa Joy Dobbins, MS, RDN, CDE -- There’s no debating it: Diabetes is a serious and growing national health ... Read More